By-Laws of the Potrero and Bay View Railroad Company, of the City and County of San Francisco:Incorporate April 4th, 1866 (Classic Reprint) Potrero and Bay View Railroad Company
Understanding Cancer from a Systems Biology Point of View: From Observation to Theory and Back starts with a basic question, why do we sometimes observe accelerated metastatic growth after resection of primary tumors? Next, it helps readers understand the systemic nature of cancer and how it affects treatment approaches and decisions. The book puts together aspects of cancer that many readers have most likely never combined, using unfamiliar, novel methods. It is a valuable resource for cancer researchers, cancer biologists, mathematicians and members of the biomedical field who are interested in applying systems biology methodologies for understanding and treating cancer. Explains the systemic nature of cancer and how it affects decisions on treatment Brings a variety of methods together, showing, in detail, the logical approach to finding answers to complex questions Discusses the theoretical underpinnings of cancer as a systemic disease, providing the reader with valuable information on applicable cases Irina Kareva received her PhD in Applied Mathematics for Life and Social Sciences in 2012 and was a Postdoctoral fellow at Center of Cancer Systems Biology (Tufts University School of Medicine). She has been working in mathematical modelling of cancer as an evolving ecological system throughout her career, focusing on understanding cancer as a complex systemic disease rather than just disease of the genes. Several of the theoretical constructs that she proposed have been subsequently independently verified experimentally. Dr. Kareva strives to incorporate knowledge from molecular biology, evolutionary ecology, mathematics, game theory and even palaeontology to find approaches to understand and treat cancer to achieve long term positive outcomes. Dr. Kareva published a book entitled Niche Construction, Sustainability, and Evolutionary Ecology of Cancer (Scholars Press, 2015) and has published in diverse important journals as Ecology and Evolution of Cancer, Journal of Theoretical Biology and Cancer Research. She was Distinguished Lecturer at Rochester Institute of Technology (2016) and speaker in some major scientific meetings, such as World Congress on Angiogenesis (2015) and 9th European Conference on Mathematical and Theoretical Biology (20140.
This book proposes a new way to think about evolution. The author carefully brings together evidence from diverse fields of science. In the process, he bridges the gaps between many different--and usually seen as conflicting--ideas to present one integrative theory named ONCE, which stands for Organic Nonoptimal Constrained Evolution. The author argues that evolution is mainly driven by the behavioral choices and persistence of organisms themselves, in a process in which Darwinian natural selection is mainly a secondary--but still crucial--evolutionary player. Within ONCE, evolution is therefore generally made of mistakes and mismatches and trial-and-error situations, and is not a process where organisms engage in an incessant, suffocating struggle in which they cant thrive if they are not optimally adapted to their habitats and the external environment. Therefore, this unifying view incorporates a more comprehensive view of the diversity and complexity of life by stressing that organisms are not merely passive evolutionary players under the rule of external factors. This insightful and well-reasoned argument is based on numerous fascinating case studies from a wide range of organisms, including bacteria, plants, insects and diverse examples from the evolution of our own species. The book has an appeal to researchers, students, teachers, and those with an interest in the history and philosophy of science, as well as to the broader public, as it brings life back into biology by emphasizing that organisms, including humans, are the key active players in evolution and thus in the future of life on this wonderful planet. Rui Diogo is an Associate Professor at Howard University College of Medicine and a member of the Resource Faculty at the Center for the Advanced Study of Hominid Paleobiology at George Washington University. One of the youngest researchers to be nominated as Fellow of the American Association of Anatomists, he won several prestigious awards, being the only researcher to be selected for the first/second place for best article of the year in the top anatomical journal two times in just three years (2013/2015). Author or co-author of more than 100 papers in top journals, such as Nature, and of numerous book chapters, he is the co-editor of three books and the sole or first author of eleven books covering subjects as diverse as fish evolution, chordate development, and human medicine and pathology, including a book adopted at medical schools worldwide, Learning and understanding human anatomy and pathology: an evolutionary and developmental guide for medical students.
This volume based on an international and interdisciplinary conference in 2014 provides an assessment of the developments after the upheavals in the Southern Mediterranean with regard to the challenges for the European Foreign and Security Policy. Besides a review of the European Neighbourhood Policy and the experiences of the European External Action Service in the countries of the Southern periphery, the analysis considers economic and social dynamics across the Mediterranean as well as challenges from societal actors, especially Islamist groups with regard to regional developments and European politics. Furthermore, the volume incorporates the view of the eminent regional actors Turkey and Israel and explains their responses towards the regional developments. With contributions by: Steffen Angenendt, Maximilian Benner, Dustin Dehez, Çagri Erhan, Burak Küntay, Baran Kusoglu, Amichai Magen, Piril Ocak, Sharon Pardo, Silvia Popp, Alessandro Quarenghi, Stephan Roll, Julia Simon und Jan ?naidauf.
The fourth edition of Jane Austen´s Letters incorporates the findings of new scholarship to enrich our understanding of Austen and give us the fullest view yet of her life and family. The biographical and topographical indexes have been updated, a new subject index has been created, and the contents of the notes added to the general index.
Written from a female and Indigenous perspective, the poems in Indianland incorporate Anishinaabemowin throughout. Lesley Belleau explores rich themes of sexuality, birth, memory, and longing, as well as touchstone issues in Indigenous politics including Elijah Harper, Murdered and Missing Indigenous Women, forced sterilizations, and Kanesatake with immediacy and intimacy. This multiform collection moves from present day to first contact and back to the present, immersing us in images of blood, plants (milkweed, yarrow, cattails), and petroglyphs, and grounding the book in the beloved land of which it speaks. Indianland is a rich and varied poetry collection. The poems are written from a female and Indigenous point of view and incorporate Anishinaabemowin throughout. Time is cyclical in this collection, moving from present day back to first contact and forward again. Themes of sexuality, birth, memory, and longing are explored. Images of blood, plants (milkweed, yarrow, cattails), and petroglyphs recur, and touchstone issues in Indigenous politics are addressed, including Elijah Harper, Murdered and Missing Indigenous Women, forced sterilizations, and Kanesatake.
Greek historiography engaged with past and present time; but how exactly did this engagement incorporate claims to knowing the future? Considering prognosis as rooted in historiographical temporalities this volume reads historians from Herodotus to Appian with a view to exploring configurations of future time in the context of ancient and modern reflections on the historical as well as the ethical and political role of historiographical practice.
This volume of Progress in Molecular Biology and Translational Science introduces emerging strategies of studying RNA structure and function using nanotechnological tools. The volume aims to provide the readers with a novel view and give them opportunities to think about how to incorporate the new technologies into their own research. This book informs and updates on strategies to take advantages of nanotechnological tools to answer to fundamental questions in RNA science Collection of reviews written by the leading scientists from the field The book covers a range of topics, from single molecule analyses using nanomaterials to gene regulation using RNA nanostructures
Sustainability in the Design, Synthesis and Analysis of Chemical Engineering Processes is an edited collection of contributions from leaders in their field. It takes a holistic view of sustainability in chemical and process engineering design, and incorporates economic analysis and human dimensions. Ruiz-Mercado and Cabezas have brought to this book their experience of researching sustainable process design and life cycle sustainability evaluation to assist with development in government, industry and academia. This book takes a practical, step-by-step approach to designing sustainable plants and processes by starting from chemical engineering fundamentals. This method enables readers to achieve new process design approaches with high influence and less complexity. It will also help to incorporate sustainability at the early stages of project life, and build up multiple systems level perspectives. Ruiz-Mercado and Cabezas book is the only book on the market that looks at process sustainability from a chemical engineering fundamentals perspective. Improve plants, processes and products with sustainability in mind; from conceptual design to life cycle assessment Avoid retro fitting costs by planning for sustainability concerns at the start of the design process Link sustainability to the chemical engineering fundamentals Dr. Ruiz-Mercado is currently leading and developing U.S. EPA research projects in areas of sustainable development for helping society, government, industry, and academia. His experience, published record, and contributions to the advancement of knowledge in research areas such as sustainability evaluation, sustainable process design and life cycle sustainability evaluation, demonstrate his capability to identify new research needs and challenges.
Wageningen Univerisity and Research Centre is known for its practical and societally relevant research in spatial development. Stakeholders currently put much emphasis on participatory processes in landscape planning procedures. This poses a special challenge for research. What role does research play in our present world characterised by complexity, competing claims and development needs, and an increased concern for climate change and environmental impact? In the book Knowledge in Action we explore different types of transdisciplinary research that scientists engage in. Depending on the societal context and the interests of local citizens, researchers apply different research approaches to optimally incorporate the various points of view in their research and promote processes enhancing dialogue and shared results. In the book authors present their research experiences: their theoretical inspiration, the research methodology applied to consult, share and collaborate with societal actors in order to create options for change. The book includes several striking examples from The Netherlands (both successful and less effective), and also innovative examples from communities in Africa and Asia. The authors reflect on opportunities, problems and dilemmas they had to deal with. They especially address how far the role and theoretical perspectives of collaborative researchers can lead them in action research. Can they limit themselves to joint knowledge production and learning processes or should they engage in strategic positioning, advocacy and entrepreneurship to make it happen? The book discusses the issues that researchers should consider when they position their research activities within ongoing developments at landscape level. Read the book and judge for yourself.